Successful application of technetium-99m-labeled octreotide acetate scintigraphy in the detection of ectopic adrenocorticotropin-producing bronchial carcinoid lung tumor: a case report.
Identifieur interne : 001726 ( Main/Exploration ); précédent : 001725; suivant : 001727Successful application of technetium-99m-labeled octreotide acetate scintigraphy in the detection of ectopic adrenocorticotropin-producing bronchial carcinoid lung tumor: a case report.
Auteurs : RBID : pubmed:20955547Abstract
The diagnostic efficacy of somatostatin receptor scintigraphy labeling with 111 indium in the localization of tumors has been assessed in a limited number of patients with contradictory outcomes. Here, we describe the case of a patient with an ectopic adrenocorticotropic hormone-producing bronchial carcinoid tumor diagnosed preoperatively using technetium-99m-labeled octreotide acetate scintigraphy.
DOI: 10.1186/1752-1947-4-323
PubMed: 20955547
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<author><name sortKey="Esfahani, Armaghan Fard" uniqKey="Esfahani A">Armaghan Fard Esfahani</name>
<affiliation wicri:level="1"><nlm:affiliation>Bushehr Research Center for Nuclear Medicine, The Persian Gulf Biomedical Sciences Institute, Bushehr University of Medical Sciences, Bushehr, Iran. assadipoya@yahoo.com.</nlm:affiliation>
<country xml:lang="fr">Iran</country>
<wicri:regionArea>Bushehr Research Center for Nuclear Medicine, The Persian Gulf Biomedical Sciences Institute, Bushehr University of Medical Sciences, Bushehr</wicri:regionArea>
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<author><name sortKey="Chavoshi, Maryam" uniqKey="Chavoshi M">Maryam Chavoshi</name>
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<author><name sortKey="Noorani, Mohammad Hadi" uniqKey="Noorani M">Mohammad Hadi Noorani</name>
</author>
<author><name sortKey="Saghari, Mohsen" uniqKey="Saghari M">Mohsen Saghari</name>
</author>
<author><name sortKey="Eftekhari, Mohammad" uniqKey="Eftekhari M">Mohammad Eftekhari</name>
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<author><name sortKey="Beiki, Davood" uniqKey="Beiki D">Davood Beiki</name>
</author>
<author><name sortKey="Fallahi, Babak" uniqKey="Fallahi B">Babak Fallahi</name>
</author>
<author><name sortKey="Assadi, Majid" uniqKey="Assadi M">Majid Assadi</name>
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<front><div type="abstract" xml:lang="en">The diagnostic efficacy of somatostatin receptor scintigraphy labeling with 111 indium in the localization of tumors has been assessed in a limited number of patients with contradictory outcomes. Here, we describe the case of a patient with an ectopic adrenocorticotropic hormone-producing bronchial carcinoid tumor diagnosed preoperatively using technetium-99m-labeled octreotide acetate scintigraphy.</div>
</front>
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<pubmed><MedlineCitation Owner="NLM" Status="PubMed-not-MEDLINE"><PMID Version="1">20955547</PMID>
<DateCreated><Year>2010</Year>
<Month>10</Month>
<Day>29</Day>
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<DateCompleted><Year>2011</Year>
<Month>07</Month>
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<Article PubModel="Electronic"><Journal><ISSN IssnType="Electronic">1752-1947</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>4</Volume>
<PubDate><Year>2010</Year>
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<Title>Journal of medical case reports</Title>
<ISOAbbreviation>J Med Case Rep</ISOAbbreviation>
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<ArticleTitle>Successful application of technetium-99m-labeled octreotide acetate scintigraphy in the detection of ectopic adrenocorticotropin-producing bronchial carcinoid lung tumor: a case report.</ArticleTitle>
<Pagination><MedlinePgn>323</MedlinePgn>
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<Abstract><AbstractText Label="INTRODUCTION" NlmCategory="BACKGROUND">The diagnostic efficacy of somatostatin receptor scintigraphy labeling with 111 indium in the localization of tumors has been assessed in a limited number of patients with contradictory outcomes. Here, we describe the case of a patient with an ectopic adrenocorticotropic hormone-producing bronchial carcinoid tumor diagnosed preoperatively using technetium-99m-labeled octreotide acetate scintigraphy.</AbstractText>
<AbstractText Label="CASE PRESENTATION" NlmCategory="METHODS">A 29-year-old Asian man presented to our hospital with the typical clinical features of Cushing's syndrome, which he had had for a duration of 18 months. The results of a biochemical evaluation revealed he had adrenocorticotropic hormone-dependent Cushing's syndrome. The results of a spiral abdominal computed tomography scan showed he had bilateral adrenal hypertrophy. A magnetic resonance image of the patient's brain showed he had a normal hypophysis. Whole body technetium-99m-labeled octreotide acetate scintigraphy was performed to check for the presence of an ectopic adrenocorticotropic hormone-producing tumor. The scan results showed a small focal increase in uptake in the lower lobe of our patient's right lung, just above his diaphragm. A spiral chest computed tomography scan also revealed a small non-specific lesion in the same region. A transthoracic biopsy was then performed. Pathological evaluation confirmed the diagnosis of a carcinoid tumor, of the adrenocorticotropic hormone-producing type. After surgical removal, the patient's symptoms resolved and significant clinical improvement was achieved.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">This case report shows that technetium-99m-labeled octreotide acetate scintigraphy can effectively detect an ectopic adrenocorticotropic hormone-producing bronchial carcinoid.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Esfahani</LastName>
<ForeName>Armaghan Fard</ForeName>
<Initials>AF</Initials>
<Affiliation>Bushehr Research Center for Nuclear Medicine, The Persian Gulf Biomedical Sciences Institute, Bushehr University of Medical Sciences, Bushehr, Iran. assadipoya@yahoo.com.</Affiliation>
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<Author ValidYN="Y"><LastName>Chavoshi</LastName>
<ForeName>Maryam</ForeName>
<Initials>M</Initials>
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<Author ValidYN="Y"><LastName>Noorani</LastName>
<ForeName>Mohammad Hadi</ForeName>
<Initials>MH</Initials>
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<Author ValidYN="Y"><LastName>Saghari</LastName>
<ForeName>Mohsen</ForeName>
<Initials>M</Initials>
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<Author ValidYN="Y"><LastName>Eftekhari</LastName>
<ForeName>Mohammad</ForeName>
<Initials>M</Initials>
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<Author ValidYN="Y"><LastName>Beiki</LastName>
<ForeName>Davood</ForeName>
<Initials>D</Initials>
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<Author ValidYN="Y"><LastName>Fallahi</LastName>
<ForeName>Babak</ForeName>
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<Author ValidYN="Y"><LastName>Assadi</LastName>
<ForeName>Majid</ForeName>
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<Language>eng</Language>
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